I just bought some braided Monster speaker wire, and may need to run it through some soffits with recessed lighting, how likely am I to get interference, and is there any recommendations besides running it another way to minimize interference?
Thanks.

here comes the bashing on monster cable from everyone. do your self a favor and take back the expensive monster cable. ther are many choices that are less expensive.

as for your ? i dont think so.

If the wire is safety rated for inwall use then it will be fine,as for how you run the wires just don't run them paralell to any power cables to prevent any electrical interference.
http://www.partsexpress.com/pe/showdetl.cfm?&Partnumber=100-654

how likely am I to get interference,

not likely at all.