OK so this is really, really weird.

Running a Shuttle SN27P2 with 3x 500GB WD drives in RAID5
X2 4200+ 65w, 2GB DDR2, fanless Geforce 7600GS
Harmony 720 with the Microsoft MCE receiver.
Windows Vista.
MediaPortal 0.2.3.0

OK so here's the issue:

Everything works just great with MediaPortal! HOWEVER, if I put my system to sleep and then wake it up sometime later, my Harmony freaks out. If I push up or down on it (or any command), it repeats the command a few times, so instead of just UP, it will register it as UP UP UP UP UP UP (usually about 5 presses worth). If I pull out the receiver and then plug it in again, it works again...until I put the system to sleep and wake it up later.

Does anyone know why this would happen? Just seems so odd, and it's driving me nuts. The odd thing is it's NOT the Harmony. I tried with the original Microsoft MCE remote when things go haywire, and the MS remote has the same problem! So something is really not working somewhere in the communication to the receiver.

Any ideas?

Thank you in advance!