There are a few 5.1 fully-wireless surround systems but they are light-weight and use a sound bar for the front three.
If you want a beefier setup that uses a traditional receiver than active monitors plus a wireless transmitter/receiver for each speaker would be the best route -- for now. Problem with active speakers is that you will need a power receptacle close to each speaker location and there will be the problem of hiding the power cord if wall mounting. Most active speakers are designed for studio use and are called near-field monitors. They have a more focused sound and drop off quickly off-axis. Something like Audioengine or Emotiva active monitors might work since they aren't truly studio monitors but a compromise between near-field and far-field. I think stuff like KRK, Behringer, Adam, and Genelec would be too focused and precise for home theater use unless it is a small room. There has been some chatter on the Emotiva boards concerning using their powered monitors in a home theater setting.
Denon AVR X7200WA, Emotiva XPR-5, Emotiva XPA-7, Sony XBR 75" 850C, Oppo BDP-103D, Roku 4.
DefTech BP7000SC (L/R), CLR3000 (C), SM55 (FH), UIW BPZ/A (SB), UIW 75 (TM).
JBL L7 (Sur), EoSone RSR 350 (RH).
PC 2.1 setup. Emotiva Stealth 6, SVS SB2000 sub, Emotiva DC-1 DAC.