Me and my wizard friend are tearing up act 2! He turned me onto the option in the options to customize your skill setup... what a godsend. Now that I am rocking breath of heaven, plus serenity with heal rune (3 sec invulnerability), seven sided strike, that gives me two options for being basically immune to any damage for 3 second intervals. This also allows me lots of options for healing myself(breath of heaven, serenity, potions, spending spirit on any skill). Lets say since, I have not died once. So, if you are like me, and didn't know this existed in the options, get in there and change it to allow you to stack your skills how you want. Can't believe I played for this long without knowing that option was there! ugh the gold i could have saved on repair costs.
Options > Gameplay > Elective Mode