I only found a few somewhat related hits on this when searching and not much detail and not on the current model. I think this may be possible, but don't understand the pros and cons.
I'm assembling a setup with an Oppo BDP-105, Integra DTR40.4, amps, ML summits/stage and Definitive in-wall surrounds. I'm trying to understand if I can bypass the Integra and just plug the other inputs into the Oppo since it has 2 HDMI in ports. I think this gives me a cleaner analog audio path so I can take advantage of the Oppo's DAC. I haven't played around with the Oppo's speaker setup yet so there may be issues there I haven't thought of. Bypassing the Integra lets me ditch my RTI remote entirely and use the Oppo's iPhone app as a remote.