My Tosh 56X81 came with contrast & brightness set to 100 (the max). It was in the "normal" mode, which is just a preset mode apparently for watching broadcast TV in a brightly lit area.
I was able to get a very good picture quickly by going into the Theater Mode first, which reduced brightness and contrast. I then further reduced them a bit, and I also reduced sharpness to about 25.
It's been said that the Theater Mode reduces Scan Velocity Modulation on the Toshiba TVs. At the time I bought my 56X81 I was advised to get into Theater Mode right away before making adjustments. The idea being that the Theater Mode settings (including any SVM reduction) would be loaded into memory along with any adjustments made (anytime you make a single adjustment, all the other current settings are loaded into memory).
Anyway, you can get a very good picture without a lot of tweaking on the Toshiba widescreens, but they are very sensitive to brightness/contrast/sharpness, so adjust those first.