I'm doing something similar in my house: the components will be on one side of the room and the speakers and TV will be on the other. I just moved into the house and haven't had time to set this up yet, as I've been getting my wired network running instead. If you're familiar with running cables, it's not hard to do if you have a basement beneath this room, which you do. It does help to have some specialty tools though, such as a right angle drill and flexible drill bits. I measure everything multiple times and ensure there is nothing in the walls (pipes, etc.) before I drill. Then I cut a hole for the box to be installed, and then drill from there downward (this is where the flexible bit comes in handy) or drill upward through the wall if I can ensure I'm drilling in the correct spot. Again, check before you drill to ensure you're not drilling through anything.
You can get HDMI connectors that fit in a wall plate, which is what I've done. I'll have a distance of over 30 feet for HDMI, but my TV is relatively small and I've used a similar distance before with no problems.