Having never delved into high end interconnects, I feel qualified to post in this thread
Years ago during the bi-wire craze, I decided to build custom speaker cables. I happened upon a good deal on Belden 1310A 14/4 wire. I removed the outer jacket to separate each wire and spun two each of the 14 gauge wires into an individual cable, giving me 4 total cables (8 wires total) for each speaker. I then spun two of the these cables together giving me 2 cables for each speaker. I then put a pretty cover over the cable and secured the end with quality plugs, heat shrink, etc. I made sure that each cable was exactly the same length.
My gear was not the highest quality (Paradigm Studio 60's and Denon 4802 at that time).
I replaced my 12g zip cord with my works of art. I am truly blessed. I could not here any difference. There may have been a difference but my ears could not tell. I did not attempt to do any AB tests because A) I did not have the equipment to do real time switching and B) I really did not care.
Maybe I used the wrong wire or did not twist them correctly? Maybe cable bridges would have helped?
I thank God that I do not have the ability to hear such changes in SQ (if they do in fact exist)!
It was a fun project but pretty much a waste of time and money.
Sorry to interrupt!