I'm right about 100 hours on my 46PZ80U as I post this.
Color temp: Normal
Color mgmt: On
Video N/R: On
Black level: Light
All the same, except for 'warm' color temp and 'dark' black level.
I really can't explain why the warm color temp looks better to me with DVDs; with TV programming, the warm setting seems to produce 'dirty' looking whites and oversaturated color, but with 'normal' color temp TV shows look just right. With DVDs, the warm setting looks more natural and the colors look good.
The black setting on 'dark' works great for DVD, but it crushes blacks too much with TV so I use 'light' for that. I'm guessing that it probably has something to do with the compression of my cable service. Go figure.
HD Size 2 - Although I do see a few artifacts on the extreme edges of the picture from time to time on this setting (not the fault of the TV, I know), I use HD2 because the majority of content I watch tends to be in 1080i, which looks better to me with no overscan.
My digital cable box (Pace 'Miami') is capable of 408i & 480p for SD and 720p & 1080i for HD and the output varies with each channel or program.
If I use HD1, the 720p programs tend to look a little bit crisper than 1080i, which tends to be look just a touch softer, almost as if it is slightly out of focus on size 1.
Vice versa when I use size 2. The 1080i programs look just right, but the 720p content seems just a little softer.
Overall, both resolutions look good on either setting, but unless my eyes deceive me or I am missing something technical, size 1 appears optimal with 720p and size 2 is optimum with 1080i.
For what its worth, SD content looks anywhere from decent to very good with the picture settings I am using.
Overall, in my subjective opinion, the settings I posted produce clean whites, great blacks, decent color and very good skin tones. I am only seeing minimal hints of false contouring, and as more time passes and I dial in the settings this only seems to be improving.
All things considered, I think it looks about as good as it is gonna get without a professional calibration.
* FYI - I do not use this display for gaming or PC, so I can't comment on any of that.