I bought this TV @ my local Best Buy for only $599.99. Incredible set for its price. First and foremost, to be on the safe side, download this break-in software in any format you please (I prefer the memory card version - easier since this set has an SD card slot and it's also an infinite loop so you don't have to worry about restarting it):http://www.eaprogramming.com/downloa...nload_main.htm
Let it break in this way for the first 50-100 hours of use. If you don't want to do this, then just use the plasma with the contrast and brightness turned down below 50 for 100-200 hours.
Don't know if you already know this, but burn-in/image retention (also known as "IR") is somewhat of a problem in plasmas, though it should be virtually nonexistent/negligable in the current ones (but always good to be safe). Breaking in a plasma will eliminate this problem so as long as you don't do something like leave a large, bright, static image on your screen for 4-6 hours straight. This would leave a "ghost" of the image either permanently (burn-in) or temporarily (IR). I'd suggest for you to acoid those black or grey bars during break-in as well.
As far as settings go, I always leave it on Cinema and just tweak the brightness and contrast to be between 80-95. You can tweek the rest to your liking.
BEst way to have it calibrated, though, is to call an ISF certified calibrator and have him use his high-tech equipment to give you the best picture you can possibly get. If you're not into forking another $300 over, then I suggest picking up an AVIA or Digital Video Essentials ( haven't done this yet but I [plan to order the DVE disc) disc for $15-$20 and use that to help calibrate your TV to get a great picture.
Enjoy your plasma!