"Worth it" depends on what your goals are. What are you trying to accomplish with your room?
If you're just looking for a low to moderate level of soundproofing (either into or out of the room), then throw up one layer of 5/8" drywall over some insulated walls and be done with it.
On the opposite end of the spectrum, if you're looking to prevent ANY sound from entering or leaving your room, then you'll need to go with wall isolation clips, hat channel, insulation, double 5/8" drywall, and Green Glue. Anything less and you won't be satisfied.
Personally, I feel that I can accept SOME sound into and out of the room, so I decided to go with hat channel on the ceiling only, staggered stud walls, glass fiber insulation, and one layer of 5/8" drywall with a solid core entry door. That's better soundproofing than most of the rooms in the rest of the house, so I think I'll be satisfied with the performance I'll get. Besides, if I ever want to add more drywall and green glue, I can do it later if I am really dissatisfied with the soundproofing in my room.
But some people do nothing at all, with one layer of 1/2" drywall and they're satisfied. It all depends on what you want to get out of your room when it's done.