take a dining room chair and put it 25.25 inches from a wall. See what it is like to walk by. I think you will discover that you will be fine. Personally I would just do two rows of 3 and have ample room, sitting against the wall on the one side is less than ideal. But then I rarely need to accommodate more than 6 people.
25" will put the listener's ears 36" or more from the side wall.
In typical use, one will enter the theater, find their seat, and plop their rear end into a seat and stay there for 1.5 to 2.0 hours. The aisles don't get that much use (as contrasted to, say, a hallway). So, you have a use ratio of a couple of seconds of aisle use to 5400 seconds of seat use.
I have 2 curved rows. 4 in front and 5 in the rear. The two end seats in the second row are pretty close to the wall but they don't get used all that much and I like the idea of having the 'staggered' seating so nobody is sitting directly in front of somone.
With the cuved front row, my aisles start at 30" and reduce to 27". I also have a (fairly large) sconce/torchiere in the vacinity that sticks about 6" off the wall. I was also worried about aisle width but it has not been a problem at all. 3 chairs in the front row really was not an option since we have a family of 4.