I agree with you about wireless. It's never something I've looked into though.
Well, running wires behind a wall is alright, but she doesn't want me running wires across the room under a rug like I did in our current place. I was a bit lazy because I didn't think we were going to be here for too long, so our current place has some pretty "conspicuous" wires running up the side of the walls.
I'm thinking I could probably turn the upstairs loft into the "movie room/office". Here's what I'm thinking: use my current 7.1 system upstairs. Run the wires into the attic to all the speakers. Mount the 2 rear surround speakers from the ceiling. I doubt a projector would work very well - the room has too much light. Hopefully snag one of those 70" Sharps at some point.
I think surround sound would be too difficult to hook up downstairs without running wires around the length of the entire floor and then mounting speakers on the staircase(???) or something along those lines. So, I'm thinking I'll have to go with just a couple of nice floor speakers, a sub, and a center channel for our second TV. I can hook up my HTPC I built upstairs and buy/build another one for downstairs (unless y'all have an idea for how I could access my music from downstairs as well).