Many of us view 3D bluRays from ISO images on hard drives using PowerDVD. Some are material we create ourselves and some are archives of discs copied under fair use.
You will need to mount the iso using either Daemon Tools lite or DVDFab Virtual Drive, but here is an important detail: DVD Fab Virtual Drive works much better with PowerDVD. When encoding the iso, if you have Daemon Tools running even just in the background, it makes your iso unreadable to PowerDVD. This plagued me for over a year when burning my own 3D creations in Sony Vegas. So either close out Daemon Tools entirely when creating your iso, or don't let it start up running at all. To close Daemon tools entirely, look for the tiny icon among those displayed on your task bar, right click on it, and close it. Better, still, command Daemon Tools to not load upon startup. Last I tried, DVDFab Virtual Drive did not give that problem, but as you note, PowerDVD is a moving target. Just be assured the problem occurs during iso creation, not during iso playback, and the problem can be solved by closing the virtual drive software during ISo creation.