For future buyers of the Origen S16V, I was able to fit a [dual slot] 980ti graphics card in my case. I had to dremel just a few millimeters off the hard drive bay as shown in the picture, but the card does barely fit with the bay still attached. Look at the thumb screw on the top hard drive bay lid, it hovers over the 980ti by about 1 millimeter.... whew.
My card is an EVGA 980ti with the reference cooler as this cooler has smaller dimensions than third party cooling, and thus, was able to fit with the bay and two hard drives installed. The motherboard I have is the Gigabyte Z170MX-Gaming 5. I chose micro ATX because it seems the very top slot for micro ATX is pcie x16, whereas full ATX has a pcie x1 slot at the very top, and the card definitely would not fit with the pcie slot moved down one row.
Last edited by brandon_k_w; 03-30-2016 at 11:02 PM.