Thanks to everyone for your input. Here's my update.
I've looked at a couple of different options, standalone whole house audio and full control system including Crestron's adigio, Niles ICS, Digilinx, Lifeware, Control4 and a few others.
For now I decided to just go with the Niles ICS for whole house audio and let the newer controls market mature a little more. For a demonstrated functionable standpoint I liked what the Digilinx and Lifeware SEEMED to offer, but the cost in my opinion was still too high. More importantly, I have major concerns about using Windows as the base technology for these systems. No one could address my major questions concerning security holes in Windows, or just potential regular upgrades/patches, etc. Let alone what happens in the future when MS drops support for that OS.
So from my standpoint, whole house audio was my initial desires anyway. The other systems really did not address that need directly, would still have to integrate other systems. I figured go with a good whole house audio system and then I could always integrate into a full control systems later once the market matures. Also, perhaps Niles may continue to add features to the ICS which would make the growth easier.