same here, i've got a dune and don't know for mede8er
1. Dune ca remember the last position of your last 200 movies seen. But : it only works with simple files (avi, mkv,...), not with ISO or structures (bdvm/video_ts).
2. don't consider Dune as music player. I can play music but the UI is so poor that in fact I don't use it. FYI there are also some music jukeboxes that are currently under development but with good results (MyDune Music HD for example)
3. dune (and mede8er too) doesn't use nfo. You will need for both to use a jukebox on your PC that will scrap and organize your collection in a nice way. For dune the most popular and simple are zappiti and yadis, but there are others. For mede8er (600/1000x3D at least) you can use Y2M, but also yadis with a special plug-in for mede8er. FYI : mede8er jukebox is very bad for managing TV series, but they are working on a new one that should correct this.
4. if your network is good, you will never see any stutter or else with a dune, whether you use smb or nfs.