LCD and plasma both have their strengths and weeknesses.
To say that all issues related to one, or the other technology, will go away with a few user adjustments is pure nonsense, however.
You likely won't be able to correct the mura effect (clouds) if your set is affected. You also won't be able to correct any of the LCD-related issues such as ghosting (yep, that 6ms response time some manufacturer claim is just not up to par with plasmas, and I DO see ghosting, to some degree, on ALL LCD TVs), reduced viewing angle (although manufacturers claim up to 170+ degree viewing angle capabilities, LCDs will typically get significantly dimmer when passed 90 degrees), and limited color gamut (no LCD manufacturer can claim, and deliver, the same color gamut as a top notch plasma TV). I'm not going to get into the black level issues, which also favor plasmas, because it has been debated enough already, on this forum.
That being said, some LCD TVs do look quite nice, and there may be one out there for you. LCD does have advantage. Namely, minimized reflections, and peak brightness, which make them a good choice for brightly lit rooms. LCDs are also generally better suited for computer and gaming applications because they are less prone to image retention (although permanent IR, under certain circumstances, is not a myth with LCDs). Bottom line, let your eyes be the judge and what may look bad for some, may look very good to you.