AVS Special Member
Join Date: Mar 2004
Location: St. Hubert, Quebec, Canada
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I auditioned the Q300 and the Focals (actually went with PSB Imagine Bs, but that's not my point here). I liked the Focals a lot for their detail, especially with well-recorded materials (though they were not forgiving of less than ideal recordings, to my ears). I found the Qs more "polite"--more forgiving than the Focals--with a nice overall sound.
Your ears have to decide, of course, but be aware the Qs and Focals are significantly different in sound, so a proper audition between the two is essential.
I'm not familiar with the sound of the Bostons in your list, though my HT has VR-M60s and VR-M50s which, after 8 years, I still love. Part of that has to do with the tweeter, though, and, if I'm not mistaken, the VSs have fabric tweeters which would lead to a different sound than my VR-Ms.
I think each on your list can give great sound, but they are fairly different from each other, so, again, auditioning is key.