I recently replaced some Nanosats in my secondary HT setup (replaced by Mirage OMD that used to be in my primary setup). My living room is average size (19 x 17 maybe?), and the nanosats just didn't cut it. They will sound better than the Bose, but you really need something bigger than microsatellites if your room is any bigger than a shoebox. I kept the 8" Nanosat sub around for awhile, but eventually decided to replace it with an inexpensive 12" sub. Since I use both of my HT setups a fair amount, I'm much happier with this arrangement.
I would try to bargain with your wife to see if you can least move up to mid-sized bookshelf speakers. You will be much happier in the long run.