5 NHT SuperZero 2.1s and a $500 sub like the SVS SB or PB 1000 would be a great system.
I had 5 of the SZ 2.0s and they were great. I upgrade because I wanted more volume and more dynamics. The SZ can get loud though, even with my 50 watt/channel AVR.
Klipsch RF-62II, RC-500, RS-400, SVS PC12+,
Def Tech SC8000
Harman Kardon AVR 1600
PS3, Apple TV, Sharp 70" Qattron