I bi-wired my KEF Q7's. I thought I heard a small improvement in midrange clarity, but I'm not sure it's a reliable observation. If it was a real change, then I'd have to say that it was much less audible than the effect of removing the grills (which was a big improvement).
AT&T U-Verse Northeast Ohio
Denon x4000, Carver m1.0t, Samsung LED TV, B&W 704 mains, two M&K subwoofers, Oppo 103, Roku 2, etc.
Headphone system: Sennheiser HD600, AKG K702, Hifiman HE-400i, Marantz HD-DAC1 (also used for music playback in the main system, Marantz CD5004, Denon DVD-3910