Thank you all very much for the information.
There are 4 speakers mounted in the ceiling - two in the living room and two in the master suite. But I think there might be three of those blue wires (each contains the black, white, red, and green strands). With 4 speakers and 3 wires, I am not sure how that would work out.
jdsmoothie, if a pair of speakers are connected to a single 4-conductor speaker wire, does Black goes with White then Red goes with Green?