For the folks wondering about YCbCr 4:4:4 vs YCbCr 4:2:2 vs Studio RGB vs Extended RGB on input and output settings in the D2 and on settings in your source and display devices:
Read the posts on "Data Format" linked in the Technology and Terminology section of the first post of this thread. Also read the "Video Calibration for non-ISF Techs" post in the Setup links.
The simple answers are:
1) DO NOT CHANGE your Video Output settings, or the video level settings in your Display, just because the input source is sending something unexpected some of the time. There is one and only one "best" output setup between the D2 and your display. It is the Anthem's job to convert any input type to that "best" output type that you specify in Setup / Video Output and that you calibrate using your display's video level controls. Setup your Anthem's Setup / Video Output first (as described in the linked posts -- using the Anthem's internally generated test patterns in the Video Source Adjust menu and using the display's own video level controls for calibration) and then setup your input source settings. Oddness from any source device needs to be corrected using the settings in the source device itself or in the Anthem's Video Source Adjust / Picture menu for that input. NOT by changing settings on the display side of things.
2) For HDMI devices your starting point should by YCbCr 4:4:4. For DVI devices your starting point should be Studio RGB (not Extended RGB), OR look for a setting in the DVI device that configures it for use with a normal home theater setup as opposed to use with computer equipment. Studio RGB may just be labeled "RGB" in a source or display device. There will be odd cases where you need to do something different from that default starting point, but start there.
3) It is almost never the case that Extended RGB is the right choice for home theater use in either a source, a display, or the Anthem. Discovering that you have to use it probably means you are fighting a bug in your source or in your display, or that you have manually (INCORRECTLY!) forced your source or display to use it instead of the Studio RGB (or just "RGB") it would normally use, or that you are using computer-style equipment which is not designed to fit in naturally in a home theater setup. Studio RGB is also sometimes indicated in source or display device menus by "Black=16", or "IRE=7.5", or "Blacks=Normal", or "Blacks=Lighter" (in sources), or "Blacks=Darker" (in displays). Unfortunately, the people who dream up these menus haven't bothered to try to all use the same terminology. The setting you are looking for will have only two choices (i.e, don't confuse it with a multi-level control such as Brightness or Contrast) and it will be named as something having to do with imaging darkness or blacks. In some cases you may have to just try both ways to try to figure out what the heck they are calling Studio RGB. Do NOT be confused by terminology such as Extended or Enhanced blacks into thinking that's what you want. The people writing that stuff in manuals are clueless. It is much more likely that what you want will be labeled "Normal".
4.1) You can't properly compare whether one of these settings is better or worse than another until you RE-CALIBRATE your basic video levels (Blacks, Whites, Colors, Sharpness) BOTH WAYS and only THEN do your A/B comparison. Selecting a different data format changes how the data is encoded and video levels need to be adjusted to compensate.
4.2) In particular, if you are seeing one setting as producing obviously darker or lighter imaging than the other in the near blacks then you have NOT yet properly re-calibrated levels both ways! The real differences between these Data Formats (i.e, after both ways are properly calibrated) is more subtle than that. Note that if you set a source or display to use the "wrong" data format, then some devices will not even give you enough video calibration control range to get things properly calibrated again. This should be a clue that you shouldn't be using that data format.
4.3) If you are changing an INPUT side data format setting, then re-calibration needs to be done using the Anthem's Video Source Adjust / Picture controls or (more likely) the video output format or level controls in the SOURCE DEVICE. Do NOT alter the settings you already have in Setup / Video Output or in your display! If you are changing an OUTPUT side data format setting, then re-calibration needs to be done using your DISPLAY'S video level controls -- based on the Anthem's internally generated test patterns in the Video Source Adjust menu. Do NOT alter the Anthem's Video Source Adjust / Picture (i.e., input) settings or your source's settings. I.e., there is a proper calibration for the output side (which should be done first) and then a completely separate calibration to fine tune things on the input side. Having to make major corrections in the Anthem's Video Source Adjust / Picture settings for some source is an indication that you have goofed up somewhere.
5) Try to keep Data Format and Color Space separate in your mind. They are different things. See the posts linked above. Unfortunately, Anthem's Video Source Adjust / Picture menu lumps the Color Space setting for YCbCr inputs and the Data Format setting for RGB inputs into the same "Input Color Space" menu. You need to check mark a setting for each of these two settings in that menu. The Anthem will automatically use the YCbCr Color Space selection if the source is sending YCbCr and will use the RGB Data Format selection if the source is sending RGB.