AVS Special Member
Join Date: Nov 2006
Location: Bushnell's Basin, NY
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If wires are run, then you have your speaker placements. To a great extent, they are what they are, a compromise as most rooms. More spacing to walls and more separation are desirable, but not deal breakers. Do what you can, and then let the AVR's room correction system do what it can with the resulting layout before coming to any judgements.
For surrounds, you don't want them co-located, so a surround soundbar only makes sense if it's got some DSP features that enhance the spatial perceptions. Just try to get them close to 90 degrees from the TV - at your side, not behind you, per THX and Dolby.
Remember that we all deal with tradeoffs; you have a nice living space, so enhance it as best you can without the enhancements intruding.