AVS Special Member
Join Date: Dec 2007
Location: Southern California
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The only real issue there is loading.
A 22,000 ohm input impedance should not be a problem with almost any preamp.
The only time you would need to be concerned is if the input impedance of the amplifier is less than two times the output impedance of the preamp.
Then the loading could be significant.
It is odd that there is no output impedance given for the preamp, but it is seldom more than 2000 ohms, so again a 22000 ohm load is not going to be a problem.
P.S.- I just talked to an engineer at Berkeley, and he says the output impedance is only 110 ohms per leg or 220 ohms total in balanced operation.
The 4.2 volts input spec for the McIntosh is probably the maximum input voltage allowable to avoid overloading the input circuit; that is also not going to be a problem. The output of your preamp will seldom exceed 1 volt, which will not overload the amplifier. There is no sound quality issue.