having been part of the beta testing for this remote and having used it for a few months now I can comment on some of the differences...
some of the differences are good news and bad news.
first the good...as you said, better screen, different color. it's subscreens are fully customizable on the left and right, allowing different buttons on each subscreen. so you could put the A B C buttons for your DVR down the left of the PVR control screen of the watch tv activity, but on the favorites subscreen on the left you can place completely different commands. it works with the wireless extender very well...in fact, unlike the 1000, it actually works very well with multiple extenders.
the bad....can't upgrade to the 1100. it requires setting up a new account from scratch. trust me, I wasn't happy about it either as we had to set up our accounts on the beta server, and then again on the live server once it moved out of the beta area. sequences are not currently on this remote. yes, activities (the basis of the harmony line) is here, but sequences are not. the technical reasons behind this have been asked to remain confidential at least for now
the so so...we had the slideshow removed. all it did was cause confusion, and people wanting to use the remote as a photo frame when in the base. the screen isn't built for that type of use and it would burn out way too quickly. like the other remotes, it doesn't work when in the charging base...again, the reasons behind this have been asked to remain confidential
IMO, it's a 'fixed' 1000 in most senses...which makes me wonder about the future of the 1000. anyone who knows me from the logitech forums knows I would never recommend the 1000. I can say that the 1100, as long as you don't need sequences, is a very solid remote.