Why pick one when you can do both? I prefer the harmony when watching directv and I am ffwd through the commercials all the time. I just prefer hard buttons. For other things like selecting a movie and watching it I like Roomie on the ipad2.
I am using Roomie only now and it is great but I do miss the hard buttons. What swings me to it is that I am using it to control 4 rooms. Being able to "turn off Kitchen" then "turn on TV in bedroom" while on my way upstairs is good.
If you are only doing a single room and want hard buttons I am selling an almost new Harmony 900 in the classifieds for $160 (I would waive the shipping if you wanted it.