I am extremely happy with this remote. The touchscreen is cool. The actual screen is hard plastic(i thought the harmony 1000 was kind of soft, like if you pressed it to hard you would make a dent in it, but I could be wrong). The screen is very responsive and I haven't made an error at all pressing it. Activites are 3 to a page and buttons.favorite channels are 6 to a page. I have not made an error pushing the wrong thing. I'm glad harmony made the buttons 6 a page. If it had been 8/page, I think more people would have difficulty pushing the right buttons.
I had the Harmony SST-659, which is similar to the One but the screen was just text (no pictures/colors). Remote displays the day and time in the screen, however, it does not display the date or am/pm. I thought this was odd since the remote actually asks you for day, month year, etc. I might have to go back and see if this can be changed in with the software.
I like the charger - very easy to charge and sits well on the charger. I heard a lot of problems with the 880, not the case with the One. Took me literally 15-20 minutes to program the remote to operate TV, receiver, Directv HD DVR, DVD, DVD recorder, VCR & Xbox 360. I had problems with my 659 always not turning on the right settings for my activities and the 4 AAA batteries would usually only last one month. The harmony One hasn't made any errors in my activites yet and no more problems with replaceing batteries. The only thing that took me long was setting up my favorite channels images. This was only becasue I went to a site that had the icons for the 880 and the resolution is better on the Harmony One so I had to play around resizing the images. The harmony software doesn't give you a lot of channel images ( only about 20-25 and no abc, cbs, etc.) The favorites, besides the channel images, were easy to setup and all work great. By the way, I have a BigTen Network button if anyone needs it.
One of my favorite features of this remote is that when just sitting on my table the remote is off. When I pick up the remote it turns it self on, pretty cool. The remote is always backlit (except when not in use or sitting on a table) and is very easy to read in the dark.
Only downside is the black glass-like finish which very easily picks up fingerprints. Logitech did provide a black cloth to clean the remote in the box.
Overall I am really happy with the remote and glad I purchased it. As I was not a 880 owner, I can't compare to it. However if I had to choose between a nice touch screen and little buttons to push on the side of a screen, I would choose the touch screen.