Yes, AMD cards like to default to significant underscan. Exactly the screen you posted a shot of.
Turning off scaling (or setting it to zero underscan, I think the same thing) and enabling 1080p60, coupled with Pixel Direct, is the secret sauce for pixel matching. Things look noticeably crisper.
However, for those using Windows Media Center, without an external player such as MPC-HC, I found that WMC doesn't output the rightmost pixel column. Quite freaky...