I just got the Wyred pre setup tonight and have been doing some listening.
I started by listening to some selected tracks with the Modwright as my pre and then switch over to the Wyred pre. Music included:
Fleetwood Mac (Very Best Of)
Eric Clapton Unplugged
Cream Of Clapton
Into the Wild Soundtrack (Eddie Vedder)
The Police (Greatest Hits)
Metallica (Master of Puppets)
Red Hot Chili Peppers (Blood Sugar Sex Magik)
Jane Monheit (Taking a Chance on Love)
311 (Greatest Hiits)
Depeche Mode (Remixes 81-04)
The Doors (Greatest Hits)
Dave Matthews (Under the Table and Dreaming)
The first thing I noticed (after the system warmed up) was a noticeably taller soundstage with the Wyred pre. Strange how that works....the speakers disperse sound at the same height, but I perceive an increase in height. Soundstage width and depth were comparable. The next thing I noticed was more prominent dynamics with the Wyred pre. The Modwright is no slouch dynamically (especially with Raytheon tubes), but the Wyred pre just sounds less restrained. Deep bass is stronger as expected, but also a bit tighter. Vocals are less full with the Wyred pre but by no means thin - just more neutral I would say. This was evident with Eddie Vedder and Jane Monheit pieces I listened to. Detail is comparable, although a little easier to pick out individual sounds with the Wyred pre due to the better dynamics I believe. Fleetwood Mac's "Tusk" was a good example of how the Wyred pre's better dynamics improved perceived detail and was absolutely thrilling to hear on this system.
So to summarize what I've heard to far, I would say that both of these preamps are very good to excellent performers in all areas. Both deliver music that is engaging and pleasing to listen to and free of any major flaws. Soundstages are comparable in depth and width, but taller with the Wyred pre. The Wyred pre wins out in dynamics, bass, slightly in detail and is overall more neutral. The Modwright wins in creating huge and enveloping vocals and a slightly warmer presentation (if that's what your system needs). I'm pretty sure the Wyred pre will be the keeper, but will give it a little more time to be sure.