In the rockband.com forums, an admin offers this general tip to deal with this issue when it happens:
Also try turning off Dolby 5.1 in the game options or bypassing your external audio system to see if this resolves the issue. If it does, try troubleshooting your audio setup to limit or resolve the issue.
When I turn the Dolby Digital off in-game, and restart a song, this does seem to correct the issue. BUT I don't want to turn off Dolby Digital, given how awesome it sounds when it's on (at least before I start getting booed in surround sound for missing so many notes.)
So, my question is: Does anyone have any experience or advice on how to "troubleshoot your audio setup to limit or resolve" the Dolby Digital/Notes Not Picking Up issue? And not necessarily specifically with an Onkyo HT-R530 receiver, but generally? Are there any known common receiver features/settings (like Audyssey, for example) that cause issues with Rock Band? Does it have to do with what dB levels speakers are set at? I'm stumped--I've tried changing a few settings but nothing seems to make a difference. And this seems like too specific / unusual of an issue that I think it's probably doubtful that Onkyo customer service would even have an answer or suggestion for me. (and from what I've read on these forums their customer service isn't great anyway)
Any insights would be appreciated!