Well, my expertise is still pretty limited
For color, if you're not actually calibrating then I would expect auto or native to give "better" results - meaning, closer to calibrated. BUT I have never measured this to confirm, which is why I say if you prefer the look or find it more natural then use what you like. "Closer to calibrated" doesn't necessarily mean your eyes won't still pick up on an annoying tint or something. I actually kinda like native myself (we were using it on my friend's D8000 before I helped him calibrate it), but all sets are a little different of course - there's really no "right" answer here.
For grayscale, I'm not sure if it makes a difference with 10pt on or off, but I would definitely advise AGAINST adjusting any of this by eye (although Larry posted an interesting technique that can be used to get rid of tints by eye here
, but I've never tried it). Otherwise, I just think it's safer to leave everything at default values. If you don't have a reason to leave 10pt on, then I suspect it's better left off.