I use these settings for a 46ex723, 2D only. I wouldn't bother with 3D on this TV.
Scene - Cinema
Picture Settings
Picture Mode: Cinema 1
Backlight: 9
Contrast: 95
Brightness: 52
Colour: 46
Hue: 0
Colour Temp: Warm 1
Sharpness: 50
NR: off
MPEG NR: off
Dot Noise Reduction: Auto
Motion Flow: Standard
Film Mode: Auto 2
Advanced Settings
All off except for:
Detail Enhancer: Medium (Good for low definition TV and VIDS)
White Balance: 0,0,0,-1,-1,0