The decision regarding how many subs is best made after you have measured the room and you only need one sub to do it. One sub in the listening position, moving the mic all over the place with REW. Paying special attention to the dips so that once certain positions are combined, the dips are taken out. That can give you useful data to help you decide. In a difficult room, more than 1 or 2 may be needed. In other rooms you might not find more very useful and you can then start putting multiple drivers in each box or whatever floats your boat.
Here is an example with just some mains + 2 corner subs overlapped:

Turns out in my room, two corner subs are slightly better than one and with the mains running down into the midbass a little I get a pretty good result. More subs in different spots don't help much. You might have a bigger room and more options, so the situation could be completely different. The key is to find out for your room then you are in a much better position to decide.
Here is an example with just some mains + 2 corner subs overlapped:

Turns out in my room, two corner subs are slightly better than one and with the mains running down into the midbass a little I get a pretty good result. More subs in different spots don't help much. You might have a bigger room and more options, so the situation could be completely different. The key is to find out for your room then you are in a much better position to decide.



























Does that make me evil... 
