I recently did just that.
The problem I encountered after the fact was that with my screen material, the Seymour Screen Excellence EN4K, you can't make out the speakers. It just casts a glow and the entire screen lights up, which is pretty cool anyway. Depending on the screen material you select, you may have better luck, but at the expense of video quality, (e.g. perforated screens). The EN4K material is such a unique weave that you can't see through any holes when looking straight on. You can only see "through" it somewhat when you stand close to it and look "down" through it. I didn't realize this until I already installed the lights and the screen. Overall, the LEDs I got from barlighting.com are awesome, and I wouldn't hesitate to recommend them for this type of application. Very bright and VERY easy to set up and get going.