Your analogy is flawed, as Orphan Black revolves around the implications of human cloning and how the subjects of such an experiment would be impacted by it, which is wholly based in science fiction.
In order to fit your Star Trek analogy, Orphan Black would have had toWarning: Spoiler! (Click to show)
establish the presence of clones and then have "Beth" and Art just go around solving crimes each week unrelated to the main story, while Sarah received only tidbits of information about the cloning conspiracy at the end of each episode. Instead, the entire drive of the story hinges on the cloning aspect, which makes it fully valid science fiction.
Science wasn't the focus of Star Trek, either. The space travel and alien races were used as a means to explore moral and ethical dilemmas in a setting removed from the present, so as to make them less potentially offensive. By your logic, a classic science fiction story like Flowers for Algernon
isn't science fiction either, because it revolves around how an experiment to artificially increase human intelligence impacts the life of the subject and how he relates to the people around him, rather than exploring the "science" behind how one might theoretically perform the experiment for real.
This topic exemplifies why science fiction has died as a genre: people's expectations of what "good" science fiction is have changed. Good science fiction doesn't need to beat viewers over the head with constant technobabble and crazy devices: the best science fiction uses futuristic technology to initialise stories that put their characters in positions that would otherwise never happen. The focus of science fiction doesn't need to be on the science; series that focus on the implications of the science are equally valid additions to the genre.
We do complain that Revolution is bad science fiction, but it isn't just the science part that's poorly executed. The characters, the dialogue, the plots, and everything else are substandard, too. If the rest of the show improved, we would probably be more forgiving of the magical nanites and other silliness.