I'll actually have 2 optical drives, 1 card reader and 2 hard drives. Will need room inside for a GTX 560 Ti.
Still haven't found anything, though it occurred to me a 4u rackmount case might work. Been searching but haven't found one I really like. Ideally it wouldn't have a front door and wouldn't be too deep. The shelf it will be on is only 17" deep. I already cut most of the back out so airflow won't be a problem even if the back of the case is flush with the back of the shelf but I wouldn't want it to hang out over the front by more than 1" or so.