Originally Posted by DaveFi
Thanks. I was looking to go a little cheaper but that motherboard looks pretty good.
Yeah, at that point you're encroaching on X79 board prices, which coupled with a 3820 will get you 40 PCI-Express 2.0 lanes from the start. However, that Gigabyte Z77 board is a premium quality board. If you do consider that Gigabyte board, keep in mind that it is an E-ATX form factor.
Using the x4 2.0 slot for the third card on a cheaper board like the one you linked might not be too detrimental, but reports like this one
show some significant losses in similar setups with certain games. I also read about people experiencing micro-stutter due to extra latency when using a card running off a x4 slot from the PCH in a multi-GPU setup, which won't really show in benchmarks. I cannot attest to the veracity of the micro-stutter claim.