Committing to a single control solution first is always the better option. If you can narrow it down to 2-3 choices, for a control system, you can usually find devices common to those.
I went with Lutron RA2 for lighting, Denon for AVR, LG for TVs, and Nuvo for distributed audio because they're all relatively popular, and designed for integration.
I have found control manufacturers' forums to be excellent resources. Use what others have used, successfully. Don't be a guinea pig. Do OpenRemote and iRule have forums?
Take CQC as an example. You go research what equipment others have used, on their forum. No brainer.