I have a windows 7 media center pc hooked up to mine and it works great. Likewise I have an Xbox 360 and it works even better as an extender (my pc can only really handle driving a 720p signal).
My only complaint is the remote does not come with native wmc codes. I also tried to program them in and they don't work reliably. So I have to use two remotes instead. One of these days I will buy a real remote!