I got my 65W850A about three weeks ago now and all is well. Very good picture out of the box. I use General, Standard and the only thing turned off is Live Color. I view my TV from about 15' and the very slight edge shadows left and right cannot be seen unless on 100% white.
I do not see the need to fully calibrate this set, but I did check a few avsforum calibration images for white and black clipping. In the darkened room that I have, I am satisfied with things as they are.
Of course, I came from a 2000 Toshiba 61" 4:3 1st generation HD TV that just would not die - that took me about a month to calibrate to my liking. So now I am sort of up to date, having changed my AVR and DVD player to 7.2 and 3D respectively. Watched Life of PI in 3D, very nice and much better than what I have seen up to now. I tried the simulated 3D as well, not bad, but not for everyday use.
I wanted to post a link to Demo world: http://www.demo-world.eu/trailers/
You can download trailers for 2d/3d HD (1080p), that were used by various TV companies at previous shows. These trailers could be used to compare what we all see. The files are in RAR format and many are in a few parts. After you unRAR them, put them on a USB key and play them from there on your TV port.
If you want to check your sound system, download some of the Dolby/DTS/THX demos. These are very short, but very good quality surround sound. Note that both ARC and Optical return can carry 5.1 audio, but neither can do 7.1, at least not from the USB port.
Have Fun and don't become a couch potato.