If you are going to use 100% for home theater than you can consider bookshelves instead of towers. Others can articulate this better than I, but when you use subs you generally send the LFE to subs and not LCR. If you are not going to listen to music, then woofers in towers are somewhat wasted. The room is quite large so you will likely need two subs (large ones). Also, and perhaps most important, the hardwood floors, walls and windows make the room very accoustically challenged. You will want area rugs, window treatments, etc to help the room. Great speakers can't overcome poor room accoustics.
Even though this journey is beginning with B&W, I want to keep my options open so I am moving this conversation to a separate thread so as to not pollute this one. I thank everyone for their help so far.