I'd probably spend 2000-2500 on speakers, 1000-1500 on a good integrated amplifier, and 500 on room treatments.
A really nice option would be the AV123 Strata Minis
. I'm not sure if the owner (Mark) is still offering a free in-home trial, but I'd definitely inquire about it, considering your price range. Other nice options in that price range would be from Totem Acoustics, Tyler Acoustics, Audio Physic, Devore Fidelity, Wharfedale Opus, Magnepan (if you have the space). I'll let others cover the more well known manufacturers.