Robert I would say yes, definitely try them there facing forward or angled to your listening position.
I have three subs. Two are in front beside my right and left speakers and one is on the side pointed toward my listening position. I don't use them all all of the time. My sealed sub sounds more realistic with music, but they pressurize the room pretty well for movies.
If I walk around the house when they are all firing, there are various buzzes and rattles in different areas. But it is not noticeable when you are sitting in the listening position because the subs drown that out.