You use two wires, connected to the +1 and -1 inserts in your Neutrik connectors (just leave the +2 and -2 slots empty). For connectors, I like to use a straight neutrik NL4 connector on the amp side and a right angle NL4 connector on the sub side, because it allows for closer placement to the wall.
SPEAKERS: 3 x DIYSG 1099's LCR; DIYSG HTM 6's and 8's surround; 4 x RSL C34E's atmos.
SUBS: 4 x UM18-22 Mini Marty's and 2 x 21DS114-4 Devastators
SIGNAL CHAIN: Denon X4400; Minidsp 2x4 HD; 2 x Jensen Iso Sub 2RX; 3 x NX6000d.