I pull WEAU in central Lacrosse (just of Cass).
My off-air setup consists of two antennas, both from Radio Shack. One is about a 75 mile range antenna pointed north, and the second is a smaller one pointed west. I use the jointenna mentioned above to combine the signal of the two antennas, but I don't think I'd need to. The JoinTenna blocks 39 on the west facing antenna. I don't worry about blocking/isolating for the other frequencies. In La Crosse, the PBS, ABC and CBS signals are so strong, that even with the interference generated by combining two signals with just a splitter/joiner, I still get good reception (the benefit of digital TV). I have found that the west facing antenna doesn't pick up the EauClaire station at all, so combining the signal with the north facing antenna doesn't really seem to generate any significant degeneration in the WEAU signal - thus the jointenna may be overkill. WEAU comes in reasonably well, but I do plan to add a pre-amp to offset the signal loss in my relatively long cable drop and the splitters I use inline. If I was installing a new antenna from scratch, I would put a decent pre-amp on the antenna you use to pick up Eau Claire.
I do have a tall, two-story house, and my view to the north is completely unobstructed, so I have an ideal situation for receiving WEAU. If you have a clear shot, you should have no trouble getting it with any variety of decent antenna selections.