I just built a box around an E-350 and I'm very happy with it. As long as you control your source material you should be fine. I have played back 1080p content without a problem with the latest Catalyst drivers on Xubuntu 11.10 and XBMC. Others have talked about problems with interlaced media and I suppose the Bobcat cores could have a problem with that but as far as HW decoding with progressive media...no worries.