I cannot give you a detailed technical response. However, based upon my experience, there are enough variables (e.g., source quality, source type, internal signal processing, etc.) that are different between one input and another that you will be much happier if you calibrate them separately. I know this means more work but you will have better PQ out of each input as a result of the effort. I do know that ISF calibration calls for each input to be calibrated separately.
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