If your grill cloths are stained or are very dirty, you can gently clean them by putting the grill cloth face down (outside face down) onto a cotton towel. From the back side, use a mild cleaner and a spray bottle and lightly clean the area, pressing down from the back side of the grill cloth onto the cotton towel. Make sure you do a spot test first to make sure if you're using a cleaner that it won't affect the cloth or the color.
I had to do this once when my dog was puppy and thought one of my speakers was a nice place to put his mark. Luckily, it only hit the grill cloth and side of the speaker cabinet.
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